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Mastema
▾Table of Contents▾
Mastema's Wrath item
Mastema's Wrath is an unlockable passive item in Mastema, a mod for The Binding of Isaac.
Description
When entering a hostile room, the enemy with the highest HP will be marked.
Killing that enemy grants +2 flat damage for the room.
If the enemy is a boss or mini-boss, the damage persists between rooms but will slowly fade away.
How to unlock?
Defeat The Lamb as 
Mastema.
Item pools
Mastema's Wrath can be found in the following item pools:
| Name | Weight |
|---|---|
| Devil Room |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| summonable | Can be summoned via  Lemegeton. |
| offensive | Can appear for  Tainted Lost. |
| nocantrip | Not available as card effects during the Cantripped! challenge. |
Special synergies
The following special synergies and interactions for Mastema's Wrath have been documented.
| Mod | Item | Synergy |
|---|---|---|
| --- | Abyss | Gives a black locust that glows red and deals 1.4x damage. |
* Note that not all possible synergies and interactions are listed here.
External links
- Check out the item description on the mod's external Wiki.
- Download Mastema from the Steam Workshop.
Infernal Covenant 
Broken Dice 
Book of Jubilees 
Torn Wings 
Bloodsplosion 
Sinister Sight