Soul of Samael is an unlockable consumable in Samael, a mod for The Binding of Isaac.

Enemies in the current room will drop souls on death.

Spawns pickup rewards for collecting a lot of souls, similar to the Reaper Bum.

Defeat Hush and complete Boss Rush as Tainted Samael.

The following special synergies and interactions for Soul of Samael have been documented.

* Note that not all possible synergies and interactions are listed here.

The following sounds are related to this consumable.

• Download Samael from the Steam Workshop.