I RULE! is an unlockable challenge in The Binding of Isaac, added in the Afterbirth DLC.
This challenge is played on Hard mode.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this challenge for the previous Repentance version, check this page instead.

Mom's Knife
Trinity Shield
The Boomerang
The Ladder
Key Piece 1
Key Piece 2

Note: this list does not include characters' default starting items.

There are no additional notes, rules, or conditions defined for this challenge.

Based on the rules set in the .xml file, the following special rooms are disabled during this challenge:

The following is unlocked for completing the I RULE! challenge: Poker Chip

Defeat Mega Satan and unlock The Negative.

• Check out the challenge description on the external Isaac Wiki.